Dataset analysis: costain

Run id 20260528-082727_data_costain_seed0 · 2026-05-28T08:28:29+00:00 · championsnet

TL;DR

Basic

rows69,202
columns80
unique_seq_hash69,202
duplicate_rows0

source_dataset distribution

sourcerowsfraction
costain69,202100.00%

label_source distribution

label_sourcerowsfraction
sort_label69,202100.00%

Label coverage

Labels per row

labels per rowrowsfractiondistribution
010.00%░░░░░░░░░░░░░░░░░░░░░░░░░░░░░░░░
130.00%░░░░░░░░░░░░░░░░░░░░░░░░░░░░░░░░
241,40459.83%████████████████████████████████
319,03227.50%██████████████░░░░░░░░░░░░░░░░░░
48,76212.66%██████░░░░░░░░░░░░░░░░░░░░░░░░░░

Per-receptor balance

Receptorbindersnon-bindersmissingmissing %bind % (of called)
R131,46121,41516,32623.59%59.50%
FcRn60069,202100.00%—
R2AH0069,202100.00%—
R2AR23,26016,85929,08342.03%57.98%
R2B23,23315,72930,24043.70%59.63%
R3AF5,99237,00626,20437.87%13.94%
R3AV0069,202100.00%—
R3B0069,202100.00%—

Profile strings

45 unique profile strings; 0 rows (0.00%) have all 8 receptors labelled.

Top 20 most common profiles

profilerowsfraction
1----0--9,37713.55%
1---0---4,9657.17%
0--1----4,6096.66%
0--110--4,5676.60%
---1-0--4,4706.46%
0---1---4,3906.34%
1--0----4,2896.20%
---110--3,9495.71%
---01---3,4314.96%
1---00--3,3164.79%
1--0-0--3,2924.76%
1--000--3,0524.41%
----10--2,7884.03%
1--00---2,5903.74%
0--11---1,8772.71%
----01--1,6262.35%
0--1-1--1,4602.11%
0----1--1,4542.10%
0--1-0--1,1051.60%
0--111--9051.31%

Sequence features

wt_length_rate1.00
canonical_aa_rate1.00
n_glyco_motif_rate0.0864
in_variable_region_only_rate1.00

Edit distance to WT

mean = 4.67, std = 1.70, median = 5, p90 = 6, p99 = 9, max = 15.

edit distancerowshistogram
01░░░░░░░░░░░░░░░░░░░░░░░░░░░░░░
1308░░░░░░░░░░░░░░░░░░░░░░░░░░░░░░
28,133██████░░░░░░░░░░░░░░░░░░░░░░░░
3-421,234████████████████░░░░░░░░░░░░░░
5-737,872██████████████████████████████
8-91,046░░░░░░░░░░░░░░░░░░░░░░░░░░░░░░
10-14604░░░░░░░░░░░░░░░░░░░░░░░░░░░░░░
15-194░░░░░░░░░░░░░░░░░░░░░░░░░░░░░░
20-290░░░░░░░░░░░░░░░░░░░░░░░░░░░░░░
30-490░░░░░░░░░░░░░░░░░░░░░░░░░░░░░░
>=500░░░░░░░░░░░░░░░░░░░░░░░░░░░░░░

Mean edit distance, by per-receptor label

Receptorbindersnon-bindersmissing
R1mean=4.95, median=6 (n=31,461)mean=4.29, median=4 (n=21,415)mean=4.64, median=5 (n=16,326)
FcRn6——mean=4.67, median=5 (n=69,202)
R2AH——mean=4.67, median=5 (n=69,202)
R2ARmean=4.05, median=4 (n=23,260)mean=4.94, median=6 (n=16,859)mean=5.01, median=5 (n=29,083)
R2Bmean=4.29, median=4 (n=23,233)mean=4.78, median=5 (n=15,729)mean=4.91, median=5 (n=30,240)
R3AFmean=4.52, median=4 (n=5,992)mean=4.39, median=5 (n=37,006)mean=5.10, median=5 (n=26,204)
R3AV——mean=4.67, median=5 (n=69,202)
R3B——mean=4.67, median=5 (n=69,202)

Read counts per receptor

Receptorn with countmeanmedianp90p99max
R152,90750.20741163275,788
R2AR40,23745.98428138164,058
R2B39,01769.06536175621,891
R3AF43,77955.71526134621,834

Sequence diversity (per-position Shannon entropy)

Overall (sampled): n=69,202, mean entropy = 0.16 bits, max position = 2.26, positions above 1 bit = 12/232, zero-entropy positions = 95.

Sequences with all 8 labels: 0 sequences.

Per receptor (binders vs non-binders)

Receptorbindersnon-binders
R1n=31,461, mean H = 0.14n=21,415, mean H = 0.15
FcRn6——
R2AH——
R2ARn=23,260, mean H = 0.15n=16,859, mean H = 0.15
R2Bn=23,233, mean H = 0.14n=15,729, mean H = 0.14
R3AFn=5,992, mean H = 0.16n=37,006, mean H = 0.14
R3AV——
R3B——